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Year : 2016  |  Volume : 1  |  Issue : 2  |  Page : 50-54

Fecoprevalence and determinants of Helicobacter pylori infection among asymptomatic children in Myanmar

1 Paediatrician, Mandalay Teaching Hospital
2 Professor, Head of Gastroenterology Department, Mandalay General Hospital
3 Consultant Paediatrician, Mandalay Children’s Hospital
4 Professor, Head of Department of Pediatrics, University of Medicine, Mandalay
5 Professor, Mandalay Children’s Hospital

Correspondence Address:
Hnin Mya Swe
Paediatrician, Mandalay Teaching Hospital

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Source of Support: None, Conflict of Interest: None

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Objective: The aim of this study was to determine fecoprevalence of Helicobacter pylori infection and find out association between Helicobacter pylori infection and its determinants among asymptomatic 6 - 12 years old school children. Methods: This study was a school-based cross-sectional analytic study involving 90 asymptomatic 6 -12 years old school children in No. (2) Basic Education High School (BEHS), Chan-Aye-Thar-San township, Mandalay. Age, gender distribution and determinants of Helicobacter pylori infection were studied. Detection of H. pylori stool antigen was performed by using monoclonal stool antigen test kit (SD BIOLINE, Korea). The fecoprevalence of H. pylori infection was enumerated. Association between Helicobacter pylori infection and its determinants was analysed. Results: Overall fecoprevalence of Helicobacter pylori infection among asymptomatic school children was 17.8%. The most prevalent age group was 6-8 years (24.2%) followed by >10-12 years (18.8%) and >8-10 years (8%). There was no significant gender preponderance in all age groups. Higher frequency of fecopositivity in children living in overcrowded houses and those who drink non-purified water were noted (p<0.001). Eleven (28.9%) from low socioeconomic status and 5 (9.6%) from middle socioeconomic status were noted to be fecopositive. There was no significant association between domestic water source and H. pylori infection. Conclusion: Helicobacter pylori infection is prevalent in asymptomatic school children in this study. Low socioeconomic status, overcrowding and drinking non-purified water were significant determinants of H. pylori fecoprevalence. This findings may lead to key insights into the transmission of H. pylori infection in developing countries and method of reducing rates of transmission of infection.

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