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Year : 2016  |  Volume : 1  |  Issue : 1  |  Page : 7-10

Diagnosis of pancreatic insufficiency in cystic fibrosis – a practical approach

1 Ghent University Hospital, Center for cystic fibrosis, 3K12D, De Pintelaan 185, 9000 Gent, Belgium
2 Belgradostr.56, B9000 Gent, Belgium

Correspondence Address:
Eddy Robberecht
Belgradostr.56, B9000 Gent
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Source of Support: None, Conflict of Interest: None

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In many cystic fibrosis (CF) centers, consultation from gastroenterologist, are not routinely taken. Yet the original name ‘cystic fibrosis of the pancreas’ illustrates the importance of the digestive system in this disease. Nutritional status, occurrence of CF related diabetes, liver involvement, morbidity and mortality are largely associated with pancreatic function. Treatment depends on treating associated conditions as well. Knowledge of exocrine pancreatic function, sufficiency or insufficiency, is therefore paramount from diagnosis on. At present the best test for this purpose is determination of fecal elastase-1, which should therefore be used in clinical practice as the compulsory companion of a positive sweat test.

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